Momager Kris Jenner is finally sharing some of her health and wellness habits — but there’s one thing she says she won’t be trying again: Ozempic.
Talk that Jenner had used the GLP-1 medication began circulating in 2023 after fans noticed she’d slimmed down, something many pointed out across a series of Instagram posts.
Ozempic is designed for people with type 2 diabetes to help manage blood sugar, though it has also become widely used off-label for weight loss.
Its mainstream surge took off around five years ago, with a growing number of public figures saying they’d used it as part of their weight-loss journey. As with any prescription medication, side effects can vary from person to person — and Jenner says her experience was bad enough that it disrupted her ability to function day-to-day.
“I did not do like an Ozempic. I tried it,” Jenner said on the SHE MD Podcast. “We tried it once when no one knew what it was, and it made me really sick,” she said.
She then shared how she followed up with her doctor after struggling with the after-effects.
‘I can’t work anymore. I can’t, I’m so sick. I’m like, nauseous,'” she told her.
After that, Jenner said she and her medical team explored different approaches until they landed on something that fit her body better.
“I realized that a peptide injection was really great for me,” Jenner revealed. “And then I follow it up with supplements.”
“And that was a game changer. That actually bought me an extra couple hours at night because I get up so early. I tend to want to go and collapse as soon as I have my last email or my last call or see my kids and have dinner and I’m done.”
The 70-year-old also said the supplements have had a noticeable impact on her appearance, including improvements to her hair, skin, and face.
Peptides are ‘are strings of molecules called amino acids, which are the building blocks of proteins,’ Web MD states. They’re made naturally in the body and work as messengers that help direct cells.
According to the American Medical Association, peptide injections have been promoted online for a range of goals such as weight loss, muscle building, recovery, and anti-aging — though experts recommend patients ‘start with a coversation with a doctor’.
As with many treatments, professionals caution that side effects are possible, and some versions haven’t been thoroughly researched.
“Some injectable peptides are not regulated and may carry real health risks,” AMA states.
In another part of the discussion, Jenner also talked about what she believes helps her maintain her appearance at 70.
She referenced the widely discussed 2025 facelift and made light of it during the conversation.
“I had a very, well-known facelift a year ago. So that was helpful,” she laughed.
While that level of cosmetic work may not be realistic for everyone, Jenner said there’s a more practical habit she prioritizes consistently: regular bloodwork.
“I get my blood drawn every three months just to keep my hormones balanced because I realized after I was 45 that was important to your physical female health,” she revealed.
Noted!