Jenny Mollen Says GLP-1 Side Effect Left Jason Biggs ‘Screaming Like It Was a Horror Movie’

Jenny Mollen has shared a frightening health scare involving a GLP-1 medication, saying her estranged husband Jason Biggs was “screaming like it’s a horror movie” as the situation unfolded.

Mollen and Biggs announced their separation in May 2026 after 18 years of marriage. The former couple, who share two children, said at the time that they remained on good terms as co-parents.

Speaking on the Let’s Talk Off Camera With Kelly Ripa podcast, Mollen discussed her experience using tirzepatide, a prescription medication that is sold in the US as Zepbound for chronic weight management and as Mounjaro for type 2 diabetes. Tirzepatide is a dual GIP and GLP-1 receptor agonist.

Zepbound is prescribed for adults with obesity, and for adults who are overweight and have at least one weight-related health problem. It is also approved for adults with moderate-to-severe obstructive sleep apnea and obesity.

“I was microdosing the GLPs. I was also taking other peptides,” Mollen said. “But I think that something happens with your period. Maybe it’s just the perimenopausal situation.”

While reflecting on an incident from June 2025, she described how things suddenly took a serious turn.

“Suddenly I was, like, hemorrhaging. It was, like, blood clots the size of dinosaur eggs. It was so scary.

“So I run to the bathroom and I am literally sitting on the toilet and I hear this plop and just blood everywhere.”

Mollen said she called Biggs for help, but according to her account, he began panicking and was ‘screaming like it’s a horror movie’.

She went on to explain that later that night, during another trip to the bathroom, she experienced a vasovagal reaction, which causes a temporary drop in heart rate and blood pressure and can reduce blood flow to the brain.

Mollen said she then ‘passed out on the floor’, adding: “I’m calling him. I’m like, ‘Jason, Oh, my God, I’m unconscious.’”

“I’m laid on the bathroom floor. Jason’s like, ‘Jenny you have to get up. You have to let me take you to the car. I’m going to take you to the emergency room,’” Mollen went on.

She said she then collapsed again before eventually being taken to hospital.

“That night was harrowing,” the actor added.

Mollen also said she had been using tirzepatide because she has hyperthyroid and is autoimmune.

She continued: “I don’t know if it was the GLP-1 necessarily. I think it was because I think it was messing with my hormones a little bit.

“I think had I stayed on it I would have been fine. But getting off it and then back on it is what screwed me.”

Heavy vaginal bleeding is not listed among the most common side effects of tirzepatide on its prescribing information, which primarily cites gastrointestinal issues such as nausea, diarrhea, vomiting and constipation. Medical experts generally advise anyone with severe bleeding, fainting or signs of anemia to seek urgent medical care.

Representatives for Eli Lilly and Company, the manufacturer of tirzepatide, as well as Biggs’ representatives, have been contacted for comment.